KAMPALA – President Yoweri Kaguta Museveni’s appointment of 13 new Permanent Secretaries has ushered in changes across key government ministries, departments and agencies, with several long-serving accounting officers making way for new faces.
The changes, announced by the Presidential Press Unit on Sunday, November 8, 2026, affect some of the country’s most strategic government institutions, including the ministries of Foreign Affairs, Defence, Public Service, Works and Transport, Agriculture, and Water and Environment.
The appointments have seen Dr Aminah Zawedde replaced by Prof. Stephen Akandwanaho as Permanent Secretary in the Ministry of ICT and National Guidance.
At the Ministry of Defence and Veteran Affairs, Edith Butuuro takes over from Rosette Byengoma, while Emmanuel Freddie Mugunga replaces Alex Kakooza in the Office of the Prime Minister.
In the Ministry of Water and Environment, Kenneth Akiri takes over from Alfred Okot Okidi, while Charles Ssentongo replaces Ambassador Patrick Mugoya at the Ministry of Foreign Affairs.
The Ministry of Public Service also gets new leadership, with Mark Sseremba replacing Catherine Bitarakwate Musingwiire.
At the Ministry of Works and Transport, Eng. Flavia Guto Bwire takes over from Bageya Waiswa, while Aggrey Wunyi replaces Edith N. Mwanje at the Ministry of East African Community Affairs.
Other changes include Betty Mutesa Cwinya-ai, who replaces Dr John Geoffrey Mbabazi at the Public Service Commission, and Maureen Kasande, who takes over from Rose N. Kafeero at the Inspectorate of Government.
At Parliament, Edward Sengonzi Damulira replaces Adolf Mwesige as Clerk to Parliament, while Barbara Namugambe takes over from Maj. Gen. David Kasura Kyomukama at the Ministry of Agriculture, Animal Industry and Fisheries.
Meanwhile, Sheeba Kyobutungi Rujoki has been appointed Permanent Secretary in the Office of the President, responsible for Science, Technology and Innovation.
The latest appointments were made under Article 174(2) of the 1995 Constitution, which empowers the President to appoint Permanent Secretaries.
In his November 5 appointment letter addressed to the Chairperson of the Public Service Commission, President Museveni directed the Commission to assess the suitability of the appointed officials and advise him accordingly.
According to the Presidential Press Unit, the changes are intended to strengthen institutional leadership, enhance administrative efficiency and improve the implementation of Government programmes and national development priorities.
The reshuffle places new administrative leadership in institutions central to Uganda’s public administration, national security, diplomacy, infrastructure development, agricultural transformation and regional integration.
The post Here are the replaced Permanent Secretaries following Museveni’s latest appointments appeared first on Watchdog Uganda.

